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Mr Luke Cascarini is a leading Consultant Oral and Maxillofacial Surgeon based in London, recognised for his expertise in temporomandibular joint (TMJ) surgery, complex jaw reconstruction and head and neck procedures. He is known for providing clear, evidence-based care while using the latest techniques and innovations in his field.
Mr Cascarini serves as the Chief of Service for Oral & Maxillofacial Surgery at the Harley Street Specialist Hospital and maintains private practices. He is also an Associate Editor of the British Journal of Oral and Maxillofacial Surgery. Lead clinician for maxillofacial in the OS Clinic with a board member status. Luke plays a pivotal part through his role as a member of the board, lead clinician for maxillofacial surgery, and his groundbreaking work in TMJ surgery, contributing to the overall success and achievements of the OS Clinic.
Mr Cascarini is dually qualified in dentistry and medicine, earning degrees from the University of Bristol and the University of Wales. His surgical training included time at the Royal College of Surgeons of England and higher training in oral and maxillofacial surgery in the South Thames region. Known in his career for developing innovative surgical techniques, Mr. Cascarini performed the UK’s first jawbone replacement using a custom 3D-printed mandible. He has also been a pioneer in using Level III jaw arthroscopy and AMPP/Lipogems treatments for jaw joint issues. He developed new free flap jaw reconstruction techniques for cancer and trauma patients.
During his time as a Registrar, Luke gained specialist expertise in:
Luke qualified in dentistry at the University of Bristol in 1995. He later studied medicine at the University of Wales College of Medicine, qualifying as a doctor in 2000. His first surgical house officer role was in Bristol, followed by work as a medical house officer in Sidcup, Kent. He registered with the General Medical Council as a physician in 2001.
He completed basic surgical training shortly afterwards, gaining experience in general surgery, emergency medicine, vascular surgery, colorectal surgery, and maxillofacial surgery. Oral and maxillofacial surgery was always his intended specialism, and he began higher surgical training in the South Thames region in 2004. He carried out much of this work at The Queen Victoria Hospital in East Grinstead and at Guy’s and St Thomas’, St George’s, and King’s College Hospital in London.
After 20 years of training, Luke became a Consultant at North West London NHS Trust. He later served as Head of Junior Doctor Training in his specialty at Guy’s and St Thomas’ NHS Trust until 2019. He now works as an honorary consultant and leads the head and neck cancer multidisciplinary team.
| Intercollegiate Royal College of Surgeons England | FRCS (OMFS) | Sept 2008 |
| Royal College of Surgeons | MRCS | Feb 2004 |
| Royal College of Surgeons England | FDSRCS | Dec 2001 |
| University of Wales College of Medicine | MBBCh | June 2000 |
| University of Bristol | BDS | June 1995 |
Luke has been central to introducing several innovative techniques into modern clinical practice. He was part of the team that performed the UK’s first jawbone replacement using a custom 3D-printed mandible and has helped develop advanced free-flap reconstruction methods for cancer and trauma patients.
He has contributed to the progression of Level III TMJ arthroscopy and has played a key role in establishing the AMPP/Lipogems regenerative approach for TMJ disorders.
Alongside his clinical work, Luke teaches internationally and is regularly invited to lecture on complex TMJ arthroscopy and reconstructive surgery.
Luke has published more than 50 peer-reviewed articles and has contributed to several major surgical textbooks. His work is widely used in training programmes and referenced internationally.
His research spans TMJ reconstruction, robotics, regenerative therapies, and clinical methodology. Key papers include work on:
Luke’s practice is built on clear guidance, thoughtful planning, and genuine patient support. He focuses on precise diagnosis, open conversations about every option, and evidence-led decisions. Whenever possible, he uses minimally invasive techniques and provides consistent support from the first consultation to full recovery. His goal is always the same: to restore comfort, function, and confidence with the right treatment for each individual.
While my involvement with Total TMJ Limited may create a potential conflict of interest, I will always strive to provide objective and unbiased information. My decisions are guided by my commitment to patient well-being. Please feel free to ask any questions and I will provide you with all the information needed to make an informed decision about your care.
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